And I really am very optimistic because what has happened against this background of all of these grave issues that we face, largely out of Stanford and colleges like Stanford, a new breed of entrepreneurs and philanthropists have emerged; the Pierre Omidyars, the Jeff Skolls, the Mark Benioffs, Larry and Sergei. Where did these people come from? When I was growing up, we didn’t have people who would make such a terrific commercial success, and then while we were still young turn their attention to the big problems of humanity. You live in a very special time. You are not only privileged because you get to go to a school like Stanford. You are privileged because around you are people who will reshape the world. And one person with a great idea can make a Google and a Google.org, and Bill Gates can make the Gates' Foundation. This is a time of grave danger but even more richer opportunities. I'll tell you a little bit about smallpox because I will never be able to be pessimistic having seen the worst disease in history eradicated. When I worked in India in 1974, most of you were not even a gleam in your parents' eyes in 1974, there were 188,000 children who died that year in India. I was in places in Bihar state where the rivers stopped running because of the bodies that were thrown into the rivers. I probably have seen 5,000 little babies die of this terrible disease which was the worst disease in history. In the last century, the one that ended nine years ago, wasn't so far away. Half a billion people died of smallpox. That's not a word-o or a typo. Half a billion died of smallpox. More people died of smallpox than any disease in history and in all the wars of history that have been recorded. It goes back to one of the biblical plagues being boils. This is a picture of Pharaoh Ramsey who died of smallpox. How do we know he died of smallpox? Because this little area of his skin, a friend of mine from CDC was asked by Anwar Sadat's widow to come and o...